New Targeted Treatment for Leukemia

Posted April 23, 2010 by Sanjoy Gupta
Categories: Science

Dear Friends

As of now,  perhaps the most dreaded  disease is cancer  which science is yet to be able to tackle in a full proof  manner.  Lots of efforts are going on all over the world, and scientists have succeeded in many specific cases.  But there is a long way to go.  Recently some groups of scientists have decided to pool their resources to attack  the dreaded disease Leukemia.

University of Auckland and Cancer Research UK’s commercialization arm, Cancer Research Technology (CRT), inked a partnership focused on the development of new targeted treatments for leukemia. The research will focus on an enzyme reportedly linked to the growth and development of leukemia cells.

The enzyme was originally discovered by scientists at the University of Birmingham. A collaboration between the Birmingham researchers and Cancer Research Technology’s discovery laboratories subsequently led to the identification of a series of compounds on which CRT and the University of Auckland’s drug discovery team will focus.

“Growing evidence is showing that targeting this important enzyme has the potential to lead us to new treatments for leukemia and potentially other cancers,” comments Professor Bill Denny, Ph.D., co-director of the Auckland Cancer Society Research Centre, School of Medicine. “The first step will be to generate improved compounds, which could ultimately move into preclinical development”.

Under the terms of the deal CRT retains exclusive rights to commercialize any resulting IP. Work at the University of Auckland will be supported by a  investment from its commercialization and knowledge transfer arm, Auckland UniServices.

Sanjoy Gupta

The Editor in Chief

The Biotech Trove’s Blog

Visit :-

The Biotech Trove Journal

The Biotech Trove

Courtesy :   http://www.genengnews.com/

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THE BIOTECH TROVE JOURNAL (TBT JOURNAL)

Posted April 22, 2010 by Sanjoy Gupta
Categories: Science

Dear Friends

We at ” Biotech Trove ”  are in the process of summoning all the eminent scientists and researches from the field of biotechnology, and all related fields of scientists to gather on a common platform.  We are inviting them to share their views on the current goings on in the field of biotechnology, and welcome them to submit their works, and books to us to be published in our Journal, or to be sold from our Blog Pages, ensuring them of their return !

The Biotech Trove Journal (TBT Journal) is an international scientific electronic journal which publishes papers from all areas related to Biotechnology. It covers from molecular biology and the chemistry of biological process to aquatic and earth environmental aspects, as well as computational applications, policy and ethical issues directly related to Biotechnology. Molecular biology, genetic engineering, microbial biotechnology, plant biotechnology, animal biotechnology, marine biotechnology, environmental biotechnology, biological processes, industrial applications, bioinformatics and others are some of the main subjects considered. Also short communications a welcomed. All contributions should be concise and written in English. Authors must assure that no part of the article has been published nor submitted for publication elsewhere.

AREA OF PUBLICATION
TBT Journal publishes papers in different areas related to biotechnology. This topics are:

  • AnimalBiotechnology
  • Biofilms
  • Bioinformatics and Biotechnology
  • Biopolicies of International Cooperation
  • Biosafety
  • Biotechnology Industry
  • Biotechnology of Human Disorders
  • Biotechnology Teaching
  • Environmental Biotechnology
  • Marine Biotechnology
  • Microbial Biotechnology
  • Molecular Biology and Genetics
  • Plant Biotechnology
  • Process Biotechnology

TEAM OF EXPERTS

The Biotech Trove Journal is,  backed by a rich team of Scientists and Scholars from Biotechnology and related fields for vetting the research papers we receive, before we publish the same in our Journal.  Before we publish, the author need to Transfer the Copyright in our favor, and in future may refer his/her work giving link to our journal. 

After we receive the papers from the research scholars/scientists, our Expert Team do the vetting of the papers in two stages.  After the successful vetting we then publish the works in our Journal

COPYRIGHT

Upon acceptance of an article by the journal, authors will be asked to transfer the copyright to The Biotech Trove Journal, which is committed to maintain the electronic access to the journal and to administer a  policy of fair control and ensure the widest possible dissemination of the information. The author can use the article for academic purposes, stating clearly the following: “Published inThe Biotech Trove Journal.

The Copyright Transfer Agreement  must be submitted as a signed scanned copy to :-biotechtrove@gmail.com.                All authors must send a copy of this document.

Looking forward to serve the Scientific Community !

Sanjoy Gupta

The Editor in Chief

Visit :-

Biotech Trove

TBT Journal

WHAT IS BIOTECHNOLOGY (BT)

Posted April 21, 2010 by Sanjoy Gupta
Categories: Science

Biotechnology involves the use of cellular and molecular processes to make useful products. By ‘cells’ one also means human cells. And guess what, we’ve been doing it since the Stone Age. We’ve used microorganisms since millennium to make useful products like bread, cheese, curds and mankind’s most profitable BT product till date – booze.

So what now? Well, over the past two decades, our understanding of biology has reached a point where we can actually program the smallest parts of organisms, their cells and biomolecules, to do what we want them to do.

Actually biotechnology is a multi-disciplinary field, a collection of various technologies, ranging from biology, physics and chemistry all the way to ‘hard’ mathematics, statistics, electronics and IT. It is truly the technology of life.

BT Applications

These are awesome and staggering in their scope and impact. Fanatics are convinced BT can accomplish anything. One tends to agree.

Here are just a few of the new BT applications

Monoclonal Antibody Technology can create highly specific antibody cells that can seek and find cancer cells and diagnose infectious diseases in humans and do it fast.

Cell Culture Technology can grow cells outside of living organisms. Its applications alone would fill a library. We can, for example, grow plant cells and harvest potent drugs from them at will.

Biosensor Technology combines biology with microelectronics, to produce astonishing detecting devices that could, in principle, perform any diagnostic test you care to name.

Recombinant DNA Technology is what really catches everyone’s fancy. We actually can modify and combine genes at the molecular level and many people don’t like that. For Recombinant Technology can literally change the face of mankind. Currently, we use it to produce new vaccines, treat some genetic diseases, develop new drugs, increase crop yields, develop biodegradable plastics and improve food nutritional value among many other things, including ‘blasphemy’ like cell cloning.

Proteomics will be used to improve existing proteins, especially enzymes, and to create proteins not found in nature. The chemical, textiles, pharmaceutical, paper, food, metal and energy industries have already benefited from cleaner, more efficient production made possible by BT.

Let’s take our first step into the big bad world of BioTech. We start with:

The Cell

Humans, like all other creatures, are made up of cells. Each of us has one hundred trillion cells (100, 000,000,000,000) in our body. With the exception of red blood cells, each of these cells has:

A Nucleus

This is where it all happens. The nucleus contains a very complex substance called Deoxyribonucleic acid, alias DNA. Your DNA is -you. It has all the information needed to build you. Your DNA decides everything – your looks, your bald head, the shape of your nose, the size of your … never mind. It determines to a large extent, when and how you will die. Your DNA is your fate.

Your fate comes from your parents who give you…

Chromosome

which look like shoelaces. Each chromosome contains the DNA for thousands of individual genes, the units of heredity. It’s a lot of information. In fact, each nucleus contains six feet of DNA.

DNA is Life. It’s made of two strands twisted around each other in a double helix. Each DNA strand contains a long sequence of four molecules – Adenine (A), Thymine (T), Guanine (G) and Cytosine (C). These four compounds – or bases – are literally the building blocks of Life. The bases on one DNA strand form interlocking pairs with bases on the opposite strand – but A pairs only with T; G pairs only with C. The Code of Life, you see, has only four letters – ATCG. Why? God knows.

Each DNA helix has millions of such base-pairs, which makes the Code very difficult to crack. DNA has two properties that are unique in the known Universe: It can duplicate itself and it can, in an exact way, control the making of proteins.

Proteins

Are indispensable components of all cell activities. Proteins are the catalysts of Life. Without proteins, Life cannot exist. Insulin for example, is a critical protein that regulates blood sugar. Protein function and structure is determined by the 50,000 to 100,000 genes that make up DNA.

Genes

Are not made by Levi Strauss. Each gene is a segment of double-stranded DNA that holds the instructions for making a specific protein. We say it ‘codes’ for a particular protein. The total set of genes in the nucleus is called a genome. A single mistake in the Genome (for eg. T in place of A) can cause genetic disaster. Virtually all major ailments have been linked to small errors in the Genome. Even death is programmed into the Genome.

Biotech Trove’s Disclaimer :  The views and opinions expressed in this article are those of the author(s) and do not reflect the views of  Biotech Trove as an entity.

Sanjoy Gupta

The Editor

Biotechtrov’s ‘ Blog


Courtesy  :  chillibreeze.com

Welcome to Biotechtrove’s Blog

Posted April 19, 2010 by Sanjoy Gupta
Categories: Science, Uncategorized

We welcome you all to the “Biotechtrove’s Blog !”

The Biotech Trove (TBT)  is an interactive platform and informative arena, created by “Genomic Valley Biotech Ltd (India)” where, students and  industry professionals can register, advertise and obtain information regarding new products, new technologies, industry news, case studies, investment opportunities and much more in the field of Biotechnology.  TBT is an online association, aimed at serving the communities of the Life Science, Biotechnology, Pharmaceutical, Medical and Clean-Tech Industries

TBT,  a portal run by a team of professionals from Biotechnology, Media, Marketing and Web Technology,  is revolutionizing the way in which the professional community finds relevant news, identifies important information, interacts with each other and researches product purchases. It’s  aim is to become the most comprehensive and trusted online destination for students , industry personnel and aspiring professionals alike in the field of Biotechnology and the related fields !

Creating Platform to Interact

For constant interactions and developing on-line and off-line “Biotechnology Community” , we keep on organizing seminars, webinair, podcasts to facilitate audio visual interactions among the information seekers and the sources of information.

This Blog

This blog is targeted at disseminating valuable information in the filed of biotechnology and related science, to student, researchers and professionals for their enrichment and advancement.  We expect an overall support from you, from all the corners to make our endeavor a success !!

Sanjoy Gupta

The Editor

Biotechtrove’s Blog

Genomic Valley Biotech Ltd.